The chemokine CCL18 characterises Pseudomonas infections in cystic fibrosis lung disease

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The chemokine CCL18 characterises Pseudomonas infections in cystic fibrosis lung disease.

Cystic fibrosis (CF) lung disease is characterised by chronic Pseudomonas aeruginosa infection and leukocyte infiltration. Chemokines recruit leukocytes to sites of infection. Gene expression analysis identified the chemokine CCL18 as upregulated in CF leukocytes. We hypothesised that CCL18 characterises infection and inflammation in patients with CF lung disease. Therefore, we quantified CCL18...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2014

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00070014